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Fertility Treatment For Women With PCOS – In Vitro Fertilization
In vitro fertilization (IVF) is not usually the first-line treatment for women with PCOS, but some will need IVF treatment to help them conceive. If this is you, don’t feel like a failure or panic. The IVF success rate with this treatment is the highest compared to previous fertility treatments of Clomifene and ovulation induction with FSH.
Common reasons why you need IVF are:
- No pregnancy success with all other fertility treatments, ie Clomid, Metformin, ovulation induction or ovulation induction and intrauterine insemination.
- When previous simpler fertility treatments have caused an exaggerated ovarian response causing 3 or more follicles to grow, increasing the risk of a multiple pregnancy if they all fertilize.
- When there are other fertility reasons that make IVF treatment necessary; such as: male factor problems with low sperm count and poor swimmers, blocked fallopian tubes or endometriosis in the pelvis
- Another common reason is increasing female age: for all women, the chances of pregnancy decrease as we age, and if you’re 37 or older, your fertility specialist may encourage you to consider IVF before 6 to 12 months pass. another treatment that might not work and then you’ll be a year older.
This next section will give you an understanding of management and care during; an IVF cycle, how you might feel, the risks and what your chances of pregnancy might be.
IVF treatment process The IVF treatment process basically involves removing the eggs (also called eggs/ova) from your ovaries and combining them with your partner’s sperm in the laboratory. Thus, instead of the fertilization of sperm and eggs in the fallopian tube, it takes place in the laboratory of a fertility clinic.
In normal human physiology each month, a mature egg grows to maturity and then ovulates. But in IVF we don’t want just one egg, we want at least three or more eggs, to give you a better chance of developing embryos.
The timeline of IVF treatment: the start of IVF treatment
Your fertility specialist and clinic will give you fertility hormone injections that will stimulate and grow your eggs in your ovary. The clinic’s nurses and doctors will monitor the ovarian response with blood tests and pelvic ultrasounds. When the follicles have the appropriate growth size (18 – 22 mm), then the decision is made to retrieve the eggs from the ovaries.
By the way, these hormone injections are the same FSH – Follicle Stimulating Hormone that is used in ovulation induction fertility treatment. Again, don’t be intimidated by these FSH injections, they are simple and the staff will show you extensively how to use them.
The recovery of eggs from IVF
The eggs are removed from the stimulated follicles in the ovary in a twenty to thirty minute procedure. You may be sedated for this with either local anesthesia or general anesthesia. Afterwards you may feel some period pain which may last for a day. The eggs are then placed with the sperm in the laboratory for fertilization to take place. Fertilized eggs divide and develop into embryos
IVF embryo transfer
Embryo transfer is a simple procedure; it takes about ten to fifteen minutes. It’s very similar to having a Pap smear, with the speculum inserted into the vagina to visualize the cervix. On this day, the best quality embryo is chosen to return to the uterus through a small plastic tube. Patients are usually advised to grow the embryos for up to 5 days, where they should have more than 100 cells per seed and have a better chance of implantation. Also, on day 5 of embryo growth, you can choose the best embryo to be transferred again.
Two weeks later you will return to the clinic for the pregnancy test and it can often feel like a very long wait.
Many women say that this is actually the hardest part of IVF treatment (the waiting time to see if the IVF treatment has been successful).
IVF Process: How You Can Feel
Passing by anyone fertility treatment it can be a rollercoaster, but more so with IVF, especially when it’s more involved, it takes more time, plus waiting for more chances of pregnancy.
So, of course, expectations tend to be higher.
You can start out excited and then end up disappointed when the pregnancy is unsuccessful, especially if you have to go through the treatment again. Therefore, it is important that you have some kind of support around you or that you have practices that help you stay focused and live and love life.
- Here are some other feelings you may have: Grumpy or irritable, especially during injections
- Headaches, especially if you are prone to them
- Swelling in the belly as the ovaries grow. Clothes can feel tight, especially after the eggs are removed for the first two weeks, many women feel that their belly is so big that people mistake them for being pregnant. This usually happens when a lot of eggs are collected from the ovary… and I’m talking about twenty or more.
- Period such as pelvic pain after egg collection and sometimes for the next two weeks
- Your breasts will feel larger and may also be tender to the touch
IVF success: What are the chances of pregnancy with in vitro fertilization treatment?
IVF offers the highest chance of pregnancy compared to all other fertility treatments for PCOS.
But it will depend on:
- your age
- Your general health, such as your weight and whether you have diabetes or insulin resistance.
- How good is the laboratory that processes your eggs, sperm and embryos at the IVF clinic you are with.
- The quality of your embryos.
- The number of embryos returned to your uterus
- Whether you may have other fertility factors, such as having a condition called endometriosis or male sperm problems that may affect your chances
Generally though your female agewhich correlates with the age of your eggs will be related to your chances of pregnancy and IVF success. The younger our age, the younger our eggs and therefore the more likely we are to get pregnant. The older we are, the older our eggs are and the less chance there is. of IVF success So you can see that for women, timing is important when it comes to acting on our fertility. Delay can lead to a worse outcome and regret.
On average, with an embryo transferred again, for women under the age of 38, the chances of pregnancy are 35 to 40%. For women over 40, the chances are less than 20%.
What are the possible side effects of IVF treatment?
IVF treatment has the same possible side effects as ovulation induction treatment with FSH. Some of the sensations may be worse because the dose of the FSH hormone is higher and therefore the ovaries will be more stimulated and larger.
The risk of multiple pregnancy is another side effect of IVF and will depend on the number of embryos transferred back into the uterus.
Myself and most fertility specialists would recommend transferring only 1 embryo. When placing 2 embryos the possibility of twins is around 20%.
Many couples tell me that they would love to complete their family by having twins. And while this may seem like a good outcome, the reality is that many IVF babies from multiple pregnancies give birth before their due date and, due to their prematurity, unfortunately, can end up with a bad outcome by developing the called brain damage Cerebral palsy.
But in general, if you need IVF, don’t be afraid. Many women with PCOS undergo IVF treatment and have a baby. Of all possible fertility treatments, it offers the greatest chance of pregnancy.
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