How Much Does The Average 8 Year Old Boy Weight What is Polycystic Kidney Disease?

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What is Polycystic Kidney Disease?

“PKD” stands for polycystic kidney disease characterized by the formation of multiple cysts on the surface of the kidney causing an increase in its size and weight. The weight of the cyst-filled kidney can reach 20-30 pounds. It is the most common hereditary kidney disorder that is passed down through families. If both parents are carriers of this disease, there is a 50% chance that the child will develop this disease, but if one parent carries it, the chance of it occurring in the child is still 25%. In this case the child does not develop it but simply passes it on to the next generation.

Forms of polycystic kidney disease

This disease comes in two forms; Autosomal dominant PKD and autosomal recessive PKD. Autosomal dominant PKD shows symptoms in adulthood, while autosomal recessive PKD shows symptoms in infancy and early childhood.

1- Autosomal dominant PKD or adult polycystic kidney disease

In autosomal dominant PKD there is a chance that a person will live for several years, so it is also called “adult polycystic kidney disease”. Symptoms of autosomal dominant PKD are abdominal pain, back and lower back pain, excessive urination at night, headache, high blood pressure, abnormal heart valves, kidney stones, nail abnormalities, sleepiness and menstruation painful etc. Some other serious conditions include hematuria, aneurysms (bulges in the walls of blood vessels), and diverticulosis (small pouches that protrude through the colon). Hematuria (blood in the urine) can be classified into microscopic and macroscopic. In microscopic hematuria, the blood spots are so small that they can only be seen through a microscope. Whereas in gross hematuria, large blood spots can be seen with the naked eye.

2- Autosomal recessive PKD or childhood PKD

Autosomal recessive PKD is a rare form caused by a mutation in the autosomal recessive PKD gene (PKHD1). Signs of this form of PKD appear before birth, so it is also called “infantile PKD”. In many cases, the child with autosomal recessive PKD develops kidney failure before reaching adulthood. The severity of this condition varies from case to case, as in some cases the baby dies after a few hours or days due to breathing difficulties or total respiratory failure. Its symptoms are high blood pressure, urinary tract infection, frequent urination, effects on the liver and spleen, low blood cell count, varicose veins and hemorrhoids (formation of masses or clamps of tissue inside the anal canal), etc. The growth factor is considered a main feature. of autosomal recessive PKD when the child shows less growth activity (smaller size) than the average growth rate.

Treatment of polycystic kidney disease

It is important to remember that there is no specific treatment for PKD. However, antibiotics can be used to reduce pain, high blood pressure and for problems related to urine. Dialysis and kidney transplantation are also used as alternative methods to prevent the severity of polycystic kidney disease.

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