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Lack of Muscle Increases Cancer Risk

Researchers from the American Cancer Society spent 16 years assessing 900,000 people cancer-free when the study began in 1982. They found that excess fat could account for 14% of all cancer deaths in men and 20% of those in women. They conclude that losing weight could prevent more than 90,000 cancer deaths each year. That’s one in six cancer deaths in the United States.

I think the researchers should have concluded that lack of muscle, rather than having too much fat, causes cancer. Your body produces millions of cancer cells every day of your life. However, your immunity must be strong enough to seek out any cancerous cells and kill them before they can begin to grow and multiply in your body. As you age, you lose your ability to kill cancer cells and germs, due to lack of muscle.

When a germ enters your body, you need to make cells and proteins called antibodies to kill those germs. However, antibodies and cells are made from protein, and the only place you can store extra protein is in your muscles. When you have big muscles, you have a source of muscle protein ready to make antibodies and cells. When you have small muscles, you have a very limited source of amino acids to make protein, and your immunity is often insufficient to kill germs.

In the same way, you need antibodies to control cancer cells, so loss of protein stores in your muscles leads to loss of antibodies and increased susceptibility to cancer.

If you are overweight, this study should encourage you to exercise more and eat less. This is the largest study ever of the association between obesity and cancer, and it is the most statistically significant. The study has more than 10 times the statistical significance of the largest previous research on the subject. It agrees with most previous studies that obesity is associated with an increased risk of cancers of the breast, uterus, colon, rectum, kidney, esophagus and gallbladder, and adds new associations between obesity and cancers of the cervix, ovaries, multiple myeloma, non-Hodgkin’s lymphoma, pancreas, liver and, in men, stomach and prostate.

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